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Sanne de Bruin Selected Research

vilobelimab

1/2022The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19.
12/2020Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial.

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Sanne de Bruin Research Topics

Disease

6COVID-19
01/2022 - 12/2020
4Critical Illness (Critically Ill)
12/2021 - 01/2020
3Pneumonia (Pneumonitis)
01/2022 - 02/2017
3Hemorrhage
01/2022 - 01/2020
3Inflammation (Inflammations)
05/2021 - 05/2020
2Infections
01/2022 - 05/2021
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2022
1Fever (Fevers)
06/2021
1Thrombosis (Thrombus)
06/2021
1Sepsis (Septicemia)
06/2021
1Disseminated Intravascular Coagulation
06/2021
1Disease Progression
05/2021
1Clinical Deterioration
05/2021
1Thromboinflammation
05/2021
1Acute-Phase Reaction
01/2021
1Dyspnea (Shortness of Breath)
12/2020
1Brain Injuries (Brain Injury)
09/2019

Drug/Important Bio-Agent (IBA)

3Complement System Proteins (Complement)IBA
05/2021 - 12/2020
2AnaphylatoxinsIBA
01/2022 - 12/2020
2vilobelimabIBA
01/2022 - 12/2020
2Monoclonal AntibodiesIBA
01/2022 - 12/2020
1EnzymesIBA
01/2022
1Hemoglobins (Hemoglobin)IBA
01/2022
1Tranexamic Acid (AMCA)FDA Link
12/2021
1Dacarbazine (DIC)FDA LinkGeneric
06/2021
1fibrin fragment D (D-dimer)IBA
06/2021
1LipopolysaccharidesIBA
06/2021
1InterleukinsIBA
05/2021
1Biomarkers (Surrogate Marker)IBA
05/2021
1AntibodiesIBA
01/2021
1Immunoglobulin G (IgG)IBA
01/2021
1CytokinesIBA
01/2021
1Oxygen (Dioxygen)IBA
12/2020
1HematinicsIBA
12/2020
1RNA (Ribonucleic Acid)IBA
05/2020
1Volatile Organic CompoundsIBA
02/2017

Therapy/Procedure

2Extracorporeal Membrane Oxygenation
01/2022 - 09/2019
2Critical Care (Surgical Intensive Care)
12/2021 - 01/2020
2Therapeutics
05/2021 - 12/2020
1Plasmapheresis
12/2020
1Blood Transfusion (Blood Transfusions)
12/2020